Met (D1246N) Protein, Active
Actual product may vary
Met (D1246N) Protein, Active
Met (D1246N) Protein, Active
Fisherbrand

Met (D1246N) Protein, Active

Active, N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N, for use in Kinase Assays.
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Catalog NumberQuantity
FIS14-81810 μg
Catalog number FIS14-818
Price (MYR)
811.00
Each
Quantity:
10 μg
Price (MYR)
811.00
Each

MET tyrosine kinase is a high-affinity receptor for hepatocyte growth factor/scatter factor. Signaling via this receptor-ligand pair has been shown to affect a wide range of biological activities, including angiogenesis, cellular motility, growth, invasion, and morphogenic differentiation. Mutations in the MET tyrosine kinase receptor have been identified in both hereditary and sporadic forms of papillary renal carcinoma and implicated in tumor growth, invasion, and metastasis.

GenBank J02958. The recombinant protein contains the amino acid substitutions A1209G and V1290L with reference toGenBank J02958. Both substitutions are reported inGenBank BU595386, BQ315895 and BQ316491.

Specifications
Formulationmg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol)50.1 kDa
Quantity10 μg
SpeciesHuman
RecombinantRecombinant
Protein TagN-terminal 6His
Expression SystemRecombinant enzyme expressed in Sf21 insect cells
Protein FormTruncated
Purity or Quality Grade≥70%
ProteinMet (D1246N), active
Unit SizeEach